Gouda, M., Abdelgawad, A., AboShabaan, H., Rizk, M., Ibrahim, A. (2024). Neglected toxocariasis among eosinophilic children: A cross-sectional study in Shibin El Kom, Menoufia Governorate, Egypt. Parasitologists United Journal, (), -. doi: 10.21608/puj.2024.263033.1235
Marwa A. Gouda; Ahmed S. Abdelgawad; Hind S. AboShabaan; Marwa Sabry Rizk; Asmaa F Ibrahim. "Neglected toxocariasis among eosinophilic children: A cross-sectional study in Shibin El Kom, Menoufia Governorate, Egypt". Parasitologists United Journal, , , 2024, -. doi: 10.21608/puj.2024.263033.1235
Gouda, M., Abdelgawad, A., AboShabaan, H., Rizk, M., Ibrahim, A. (2024). 'Neglected toxocariasis among eosinophilic children: A cross-sectional study in Shibin El Kom, Menoufia Governorate, Egypt', Parasitologists United Journal, (), pp. -. doi: 10.21608/puj.2024.263033.1235
Gouda, M., Abdelgawad, A., AboShabaan, H., Rizk, M., Ibrahim, A. Neglected toxocariasis among eosinophilic children: A cross-sectional study in Shibin El Kom, Menoufia Governorate, Egypt. Parasitologists United Journal, 2024; (): -. doi: 10.21608/puj.2024.263033.1235
Neglected toxocariasis among eosinophilic children: A cross-sectional study in Shibin El Kom, Menoufia Governorate, Egypt
Articles in Press, Accepted Manuscript, Available Online from 15 March 2024
2clinical pathology department, National Liver Institute, Menoufia University
3Clinical Pathology Department, National Liver Institute, Menoufia University, Shebin El-Kom, Menoufia, ,Egypt
4Department of hepatology, gastroenterology and nutrition, National Liver Institute, Menoufia University, Menoufia, Egypt
51Department of Clinical and Molecular Parasitology, National Liver Institute, Menoufia University, Menoufia, Egypt
Abstract
Background: Determination of the prevalence of human toxocariasis is a priority considering the sustained developmental goals of WHO by 2030 and the recent climatic changes. Objective: To detect the seroprevalence of toxocariasis among eosinophilic children in Shibin El Kom, Menoufia Governorate, Egypt. Subjects and Methods: The study included 300 randomly selected eosinophilic children for whom stool analysis was performed. Ninety-six of the children positive for other parasitic infections were excluded from the study to avoid cross-reactivity. The remaining 204 children with negative stool analysis were subjected to the detection of Toxocara antibodies using ELISA. Results: Seropositivity of Toxocara antibodies among examined children was 15.7% (32/204), and 84.3% (172/204) were negative. Their ages ranged from 5 to 17 years, with a mean age of 9.16±3.11 years. Suspicious clinical history was recorded in 94.1% (192/204) of children; 15.7% (32/204) had a history of recurrent fever of unknown origin, 21.6% (44/204) children were asthmatic, and cutaneous manifestations were observed in 2% (4/204) of cases. None of the patients had ocular or hepatic disorders. The history of direct contact with pets was present in 15.7% (32/204) of patients with non-significant differences to negative children. Conclusion: Our study reported a relatively higher prevalence of seropositivity to toxocariasis among children with eosinophilia in Shibin El Kom City, Menoufia Governorate, Egypt. Therefore, implementing studies on a larger scale would provide more knowledge on the spread of this parasite in Egypt, and enhance advanced approaches to improve its control.