Omics: Applications related to diagnosis, treatment, prevention and control of parasitic diseases. Part II. Helminths

	Omics: Applications related to diagnosis, treatment, prevention and control of parasitic diseases. Part II. Helminths
Article 5, Volume 15, Issue 3, December 2022, Page 256-265 PDF (422.23 K)
Document Type: Review Article
DOI: 10.21608/puj.2022.177647.1197
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Authors
Radwa Diab; Salwa Younis
Medical Parasitology Department, Faculty of Medicine, Alexandria University, Egypt
Abstract
Landscape genomic studies can help define the role of geography and ecology in the clinical presentation of parasitic diseases, and consequently provide the choice for accurate diagnosis, novel therapeutic regimens, and effective strategies for control and elimination. In this regard, RNA interference technology combined with phenotypic studies can pinpoint exactly the incriminated molecules and/or pathways that might help in identification of novel drug targets and promising vaccine candidates. Previously, we discussed the applications of omics and bioinformatics in diagnosis, treatment, and control of malaria, one of the major health problems and causes of death worldwide[1]. In the present part, we intend to unravel the complexity of genomic and post genomic implications in the pathogenesis of helminthic diseases aiming to develop and design new therapeutic drugs and/or protective vaccines against helminths diseases.
Keywords
bioinformatics; drug target; helminths; omics; parasitic diseases; vaccine candidate


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