Ekici, A., Timuçin, D., Gürbüz, E., Ünlü, A., Aydemir, S., Yilmaz, H. (2021). Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey. Parasitologists United Journal, 14(1), 34-38. doi: 10.21608/puj.2021.49914.1093
Abdurrahman Ekici; Damla Timuçin; Esra Gürbüz; Ahmet Ünlü; Selahattin Aydemir; Hasan Yilmaz. "Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey". Parasitologists United Journal, 14, 1, 2021, 34-38. doi: 10.21608/puj.2021.49914.1093
Ekici, A., Timuçin, D., Gürbüz, E., Ünlü, A., Aydemir, S., Yilmaz, H. (2021). 'Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey', Parasitologists United Journal, 14(1), pp. 34-38. doi: 10.21608/puj.2021.49914.1093
Ekici, A., Timuçin, D., Gürbüz, E., Ünlü, A., Aydemir, S., Yilmaz, H. Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey. Parasitologists United Journal, 2021; 14(1): 34-38. doi: 10.21608/puj.2021.49914.1093
Investigation of the relationship between schizophrenia and toxoplasmosis in Van province, Turkey
1Departments of Parasitology, Van Yüzüncü Yıl University, Faculty of Medicine
2SBÜ Van Training and Research Hospital for Mental and Neurological Diseases
3SBÜ Van Training and Research Hospital for Mental and Infectious Diseases and Clinical Microbiology
4SBÜ Van Training and Research Hospital for Mental and , Van Yüzüncü Yıl University, Gevaş Vocational School ,Van, Turkey
Abstract
Background: Schizophrenia is a worldwide, serious neuropsychiatric disorder of unknown cause. Previous studies showed that infectious agents may play a role in its etiology. Among them, T. gondii was strongly hypothesized. Objectives: The aim of this study was to determine the IgG and IgM seroprevalence of T. gondii in schizophrenia patients. Subjects and Methods: The study was conducted on 190 patients diagnosed with schizophrenia in Van province, Turkey. Also included as the control group were 100 healthy individuals. Anti-T. gondii IgG and IgM antibody positivity was determined by enzyme-linked immunosorbent assay (ELISA) in blood samples taken from both groups. Results: Anti-T. gondii IgG antibody was detected in 120 schizophrenic patients (63.2%), and in 100 (29%) healthy controls. Anti-T. gondii IgM antibody seropositivity was not detected in either group. Conclusion: In line with the data obtained in the study carried out in Van province, it was concluded that individuals infected with T. gondii were more likely to develop schizophrenia. Further studies are recommended to prove the relationship between T. gondii and schizophrenia.
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