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Parasitologists United Journal
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Cakir, F., Bilden, A., Ozcan, N., Cicek, M. (2022). Contested role of procalcitonin and C-reactive protein in the diagnosis of fascioliasis. Parasitologists United Journal, 15(1), 117-120. doi: 10.21608/puj.2022.117557.1148
Fatih Cakir; Alican Bilden; Nida Ozcan; Mutalip Cicek. "Contested role of procalcitonin and C-reactive protein in the diagnosis of fascioliasis". Parasitologists United Journal, 15, 1, 2022, 117-120. doi: 10.21608/puj.2022.117557.1148
Cakir, F., Bilden, A., Ozcan, N., Cicek, M. (2022). 'Contested role of procalcitonin and C-reactive protein in the diagnosis of fascioliasis', Parasitologists United Journal, 15(1), pp. 117-120. doi: 10.21608/puj.2022.117557.1148
Cakir, F., Bilden, A., Ozcan, N., Cicek, M. Contested role of procalcitonin and C-reactive protein in the diagnosis of fascioliasis. Parasitologists United Journal, 2022; 15(1): 117-120. doi: 10.21608/puj.2022.117557.1148

Contested role of procalcitonin and C-reactive protein in the diagnosis of fascioliasis

Article 13, Volume 15, Issue 1, April 2022, Page 117-120  XML PDF (315.35 K)
Document Type: Original Article
DOI: 10.21608/puj.2022.117557.1148
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Authors
Fatih Cakir* 1; Alican Bilden2; Nida Ozcan3; Mutalip Cicek4
1Departments of Medical Microbiology , Faculties of Medicine, Dicle University, Diyarbakır
2Departments of Parasitology , Faculties of Medicine, Ahi Evran University, Kırşehir , Turkey
3Departments of Medical Microbiology Faculties of Medicine, Dicle University, Diyarbakır
4Departments of Medical Parasitology , Faculties of Medicine, Ahi Evran University, Turkey
Abstract
Background: Procalcitonin (PCT) and C-reactive protein (CRP) are acute phase reactants indicating
inflammation, particularly in bacterial infections. High PCT or CRP levels were proposed in malaria,
invasive amoebiasis, babesiosis and schistosomiasis. Since liver is the sole habitat, it was hypothesized
that PCT and CRP may have a role in the diagnosis of fascioliasis.
Objective: The study aimed to investigate whether PCT and CRP have a role in the diagnosis of fascioliasis.
Subjects and Methods: Fifty fascioliasis patients and 50 healthy blood donors in the same age range, as
the control group, were included in the study. Fascioliasis was diagnosed by anti-Fasciola IgG ELISA, in
addition, direct stool examinations (fresh smear and after sedimentation) were performed in both groups.
Serum PCT and CRP levels were determined by I-chroma kits on I- CHROMA™ II device, and NFL BN-II
immunonephelometry system, respectively.
Results: There was no statistically significant difference of PCT and CRP values between the fascioliasis
patient group and the control group (P> 0.05).
Conclusion: It was concluded that PCT and CRP were not relevant parameters for diagnosis of fascioliasis
Keywords
diagnosis; fascioliasis; procalcitonin; C-reactive protein
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